How was ERBITUX shown to work?
In laboratory studies, ERBITUX was shown to:
ERBITUX can block one of the signals that tells a tumor cell to grow by attaching to a structure on the cell called the EGFR. This structure is found on both normal cells and tumor cells.
ERBITUX can form a bridge between a tumor cell and an immune cell when it is attached to the EGFR on the tumor cell. As a result, the immune cell can begin a response against the tumor cell.